4'‐(2‐Butyl‐4‐chloro‐5‐formylimidazol‐1‐ylmethyl)biphenyl‐2‐carbonitrile | Zendy

Yathirajan Hemmige S. | Zendy; Nagaraj Basavegowda | Zendy; Nagaraja Padmarajaiah | Zendy; Narasegowda Rajenahally S. | Zendy; Bolte Michael | Zendy

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4'‐(2‐Butyl‐4‐chloro‐5‐formylimidazol‐1‐ylmethyl)biphenyl‐2‐carbonitrile

Author(s) -

Yathirajan Hemmige S.,

Nagaraj Basavegowda,

Nagaraja Padmarajaiah,

Narasegowda Rajenahally S.,

Bolte Michael

Publication year - 2005

Publication title -

acta crystallographica section e

Language(s) - English

Resource type - Journals

ISSN - 1600-5368

DOI - 10.1107/s1600536805009487

Subject(s) - imidazole , ring (chemistry) , biphenyl , chain (unit) , chemistry , crystallography , stereochemistry , bond length , medicinal chemistry , crystal structure , organic chemistry , physics , astronomy

The title compound, C 22 H 20 ClN 3 O, (I), is used as an intermediate for the synthesis of the antihypertensive drug losartan. Bond lengths and angles are unexceptional. The crystal packing is stabilized by one C—H·O and one C—H·N contact. It is noteworthy that (I) is isomorphous with a closely related compound which differs in having a but‐2‐enyl chain instead of a butyl chain on the imidazole ring.

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