Open Access(3 R ,4 R ,5 S )‐5‐(Acetamidomethyl)‐ N ‐benzyl‐3,4‐dihydroxytetrahydrofuran‐3‐carboxamide
Author(s) -
Punzo Francesco,
Watkin David J.,
Iezzi Simone Michela,
Fleet George W. J.
Publication year - 2005
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536805001467
Subject(s) - dipeptide , isostere , furan , hydrogen bond , peptidomimetic , chemistry , carboxamide , intermolecular force , stereochemistry , crystal structure , crystallography , amino acid , organic chemistry , molecule , peptide , biochemistry
The title compound, C 15 H 20 N 2 O 5 , is the first example of a branched tetrahydrofuran sugar amino acid dipeptide isostere incorporated into a peptidomimetic. The crystal structure contains intermolecular N—H⋯O and O—H⋯O hydrogen bonds.