Open Access5‐Fluorouracil–dimethylformamide (2/1)
Author(s) -
Hulme Ashley T.,
Tocher Derek A.
Publication year - 2004
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536804022263
Subject(s) - uracil , monoclinic crystal system , chemistry , dimethylformamide , amide , crystallography , stereochemistry , crystal structure , biochemistry , dna , solvent
A solvate of 5‐fluorouracil with dimethylformamide (DMF), 2C 4 H 3 FN 2 O 2 ·C 3 H 7 NO, is reported. It crystallizes in the monoclinic space group P 2 1 / n , with two molecules of 5‐fluorouracil and one molecule of DMF in the asymmetric unit. This solvate exhibits a sheet structure, with the DMF molecules present on both surfaces of the sheet and 5‐fluorouracil molecules within the sheath of DMF molecules.
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