Open Access5‐Fluorouracil–1,4‐dioxane (4/1)
Author(s) -
Hulme Ashley T.,
Tocher Derek A.
Publication year - 2004
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536804022251
Subject(s) - 1,4 dioxane , fluorouracil , medicine , chemistry , organic chemistry , chemotherapy
A solvate of 5‐fluorouracil with 1,4‐dioxane, 4C 4 H 3 FN 2 O 2 ·C 4 H 8 O 2 , is reported. It crystallizes in the triclinic space group P . Two molecules of 5‐fluorouracil are present in the asymmetric unit, together with one‐half molecule of 1,4‐dioxane, which lies on a centre of symmetry. In the crystal structure, ribbons of 5‐fluorouracil molecules are joined by 1,4‐dioxane‐mediated interactions, forming sheets parallel to the (21) planes.