Open AccessRecent advances in the CRANK software suite for experimental phasing
Author(s) -
Pannu Navraj S.,
Waterreus WillemJan,
Skubák Pavol,
Sikharulidze Irakli,
Abrahams Jan Pieter,
de Graaff Rudolf A. G.
Publication year - 2011
Publication title -
acta crystallographica section d
Language(s) - English
Resource type - Journals
ISSN - 1399-0047
DOI - 10.1107/s0907444910052224
Subject(s) - phaser , crank , software suite , software , suite , diffraction , computer science , wavelength , anomalous scattering , optics , algorithm , physics , computational science , artificial intelligence , programming language , motion (physics) , archaeology , history
For its first release in 2004, CRANK was shown to effectively detect and phase anomalous scatterers from single-wavelength anomalous diffraction data. Since then, CRANK has been significantly improved and many more structures can be built automatically with single- or multiple-wavelength anomalous diffraction or single isomorphous replacement with anomalous scattering data. Here, the new algorithms that have been developed that have led to these substantial improvements are discussed and CRANK's performance on over 100 real data sets is shown. The latest version of CRANK is freely available for download at http://www.bfsc.leidenuniv.nl/software/crank/ and from CCP4 (http://www.ccp4.ac.uk/).