Open AccessOptimization of data collection taking radiation damage into account
Author(s) -
Bourenkov Gleb P.,
Popov Alexander N.
Publication year - 2010
Publication title -
acta crystallographica section d
Language(s) - English
Resource type - Journals
ISSN - 1399-0047
DOI - 10.1107/s0907444909054961
Subject(s) - data collection , computer science , completeness (order theory) , software , data mining , plan (archaeology) , noise (video) , algorithm , statistics , mathematics , artificial intelligence , programming language , mathematical analysis , archaeology , image (mathematics) , history
To take into account the effects of radiation damage, new algorithms for the optimization of data‐collection strategies have been implemented in the software package BEST . The intensity variation related to radiation damage is approximated by log‐linear functions of resolution and cumulative X‐ray dose. Based on an accurate prediction of the basic characteristics of data yet to be collected, BEST establishes objective relationships between the accessible data completeness, resolution and signal‐to‐noise statistics that can be achieved in an experiment and designs an optimal plan for data collection.