Open AccessCarrying out an optimal experiment
Author(s) -
Dauter Zbigniew
Publication year - 2010
Publication title -
acta crystallographica section d
Language(s) - English
Resource type - Journals
ISSN - 1399-0047
DOI - 10.1107/s0907444909038578
Subject(s) - phaser , compromise , context (archaeology) , experimental data , computer science , quality (philosophy) , resolution (logic) , data quality , diffraction , algorithm , data mining , mathematics , statistics , artificial intelligence , engineering , optics , physics , geology , operations management , political science , paleontology , metric (unit) , quantum mechanics , law
Diffraction data collection is the last experimental stage in structural crystallography. It has several technical and theoretical aspects and a compromise usually has to be found between various parameters in order to achieve optimal data quality. The influence and importance of various experimental parameters and their consequences are discussed in the context of different data applications, such as molecular replacement, anomalous phasing, high‐resolution refinement or searching for ligands.