Open Access`How does my CIF become a printed paper?'
Author(s) -
Brian McMahon
Publication year - 1993
Publication title -
acta crystallographica section c
Language(s) - English
Resource type - Journals
eISSN - 1600-5759
pISSN - 0108-2701
DOI - 10.1107/s0108270193000800
Subject(s) - intramolecular force , hydrogen bond , side chain , chemistry , crown ether , ether , ring (chemistry) , stereochemistry , medicinal chemistry , ion , organic chemistry , molecule , polymer
In the acid (I) (19-chloro-3,6,9,12,15pentaoxabicyclo[15.3.1]henicosal(21),17,19-trien-21-yloxyacetic acid} there exists an intramolecular O--H... 0 hydrogen bond [O... 0 2.658(3) ], which is achieved with considerable distortion of the macrocycle ring. The macroring of the ethyl ester (2) has an essentially undistorted crown ether conformation, in which the side chain overhangs the macrocycle cavity with the carbonyl O atom directed exo. Comment. As part of a programme of study of synergism in ion binding between strategically placed functional groups and macrocyclic receptors, we have studied crown ethers with pendant phenolic groups and have demonstrated cooperation ...