Open Access(2 R *,4 S *)‐2‐(Pyridin‐3‐yl)‐2,3,4,5‐tetrahydro‐1 H ‐1‐benzazepin‐4‐ol: a three‐dimensional framework built from O—H...N, C—H...O and C—H...π(arene) hydrogen bonds
Author(s) -
Gómez Sandra L.,
Palma Alirio,
Cobo Justo,
Glidewell Christopher
Publication year - 2011
Publication title -
acta crystallographica section c
Language(s) - English
Resource type - Journals
eISSN - 1600-5759
pISSN - 0108-2701
DOI - 10.1107/s010827011101016x
Subject(s) - ring (chemistry) , hydrogen bond , chemistry , stereochemistry , crystallography , molecule , organic chemistry
The title compound, C 15 H 16 N 2 O, crystallizes in the space group P 2 1 2 1 2 1 with Z ′ = 1. The seven‐membered ring adopts a chair‐type conformation with the hydroxy and pyridyl substituents in equatorial sites. Molecules are linked into a three‐dimensional framework structure by a combination of O—H...N, C—H...O and C—H...π(arene) hydrogen bonds, but N—H...O and N—H...π(arene) interactions are absent from the structure. Comparisons are made with some related compounds.