Open AccessIns and Outs of E2Fs
Author(s) -
Nancy A. Eckardt
Publication year - 2002
Publication title -
the plant cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.324
H-Index - 341
eISSN - 1532-298X
pISSN - 1040-4651
DOI - 10.1105/tpc.141210
Subject(s) - biology , e2f , mitosis , cell cycle , gene , microbiology and biotechnology , transcription (linguistics) , transcription factor , cell , cancer research , genetics , linguistics , philosophy
Precise control of the mitotic cell cycle is a critical feature of eukaryotic life. In humans, mutations in cell cycle regulatory genes lead to the uncontrolled cell proliferation and tumor formation associated with the most dreaded of all diseases, cancer. E2F transcription factors are key
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