Fructose 2,6-Bisphosphate Inhibition of Phosphoglucomutase
Author(s) -
Cynthia M. Galloway,
W. M. Dugger,
C. C. Black
Publication year - 1988
Publication title -
plant physiology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.554
H-Index - 312
eISSN - 1532-2548
pISSN - 0032-0889
DOI - 10.1104/pp.88.4.980
Subject(s) - fructose 2,6 bisphosphate , phosphoglucomutase , fructose , chemistry , biochemistry , biology , enzyme , glycolysis , phosphofructokinase
Fructose 2,6-bisphosphate inhibits phosphoglucomutase noncompetitively with respect to the cofactor glucose 1,6-bisphosphate. Previous studies from our laboratory had shown that phosphoglucomutase was activated by fructose 2,6-bisphosphate in the absence of added glucose 1,6-bisphosphate. The fructose 2,6-bisphosphate activation previously reported was due to the presence of glucose 1,6-bisphosphate in the commercial preparation of fructose 2,6-bisphosphate.
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