Evidence for the Occurrence of, and Possible Physiological Role for, Cyanobacterial Calmodulin | Zendy

Geoffrey W. Kerson | Zendy; Ján A. Miernyk | Zendy; Kenneth Budd | Zendy

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Evidence for the Occurrence of, and Possible Physiological Role for, Cyanobacterial Calmodulin

Author(s) -

Geoffrey W. Kerson,

Ján A. Miernyk,

Kenneth Budd

Publication year - 1984

Publication title -

plant physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.554

H-Index - 312

eISSN - 1532-2548

pISSN - 0032-0889

DOI - 10.1104/pp.75.1.222

Subject(s) - calmodulin , ethanol , chemistry , oscillatoria , radioimmunoassay , biochemistry , cyanobacteria , biophysics , biology , enzyme , bacteria , genetics

Phosphate uptake by the blue-green alga Oscillatoria limnetica Lemmerman is stimulated by micromolar concentrations of Ca(2+). The calmodulin antagonists 4-(3-[2(trifluoromethyl)phenylthiazin-10-yl]propyl)-1-piperazine ethanol-HCl and its monofluoro-analog inhibit orthophosphate uptake of Oscillatoria limnetica by over 97% implying involvement of calmodulin in this process. A calmodulin-like protein was quantitated in cell-free extracts from O. limnetica by radioimmunoassay.

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