Crown Gall Tumor Disc Bioassay | Zendy

Alan G. Galsky | Zendy; James P. Wilsey | Zendy; Richard G. Powell | Zendy

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Crown Gall Tumor Disc Bioassay

Author(s) -

Alan G. Galsky,

James P. Wilsey,

Richard G. Powell

Publication year - 1980

Publication title -

plant physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.554

H-Index - 312

eISSN - 1532-2548

pISSN - 0032-0889

DOI - 10.1104/pp.65.2.184

Subject(s) - gall , bioassay , bacteria , crown (dentistry) , cytotoxic t cell , biology , in vitro , tumor cells , botany , microbiology and biotechnology , chemistry , biochemistry , cancer research , ecology , genetics , medicine , dentistry

Seventeen samples consisting of purified compounds and various ethanol extracts from plant sources were tested for activity on the initiation of crown gall tumors on potato discs. The results demonstrated definite correlation between the ability of these samples to inhibit the formation of crown gall tumors and their activity on the P388 leukemia system in mice. Samples showing only cytotoxic effects in KB cell cultures did not affect tumor initiation in our system. The active materials had no effects on bacterial viability or on the ability of the bacteria to attach to a tumorbinding site.

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