Conceptual Developments in Metabolic Control, 1924-1974
Author(s) -
Harry Beevers
Publication year - 1974
Publication title -
plant physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.554
H-Index - 312
eISSN - 1532-2548
pISSN - 0032-0889
DOI - 10.1104/pp.54.4.437
Subject(s) - nad+ kinase , glycolysis , metabolic control analysis , control (management) , biochemistry , control of respiration , sketch , catabolism , chemistry , biology , enzyme , computational biology , computer science , respiration , botany , microbiology and biotechnology , algorithm , artificial intelligence , insulin
A brief sketch is given of the development of the understanding of the respiratory mechanism in plants over the past 50 years. Against this background the following aspects of control are discussed: (a) nonreversibility of catabolic sequences; (b) compartmentation of reactions and reactants; (c) control by amount of enzyme; (d) control by NAD and NADP; (e) control by ADP supply; (f) pacemaker reactions in glycolysis; and (g) control at branch points: further examples of allostery.
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