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The Influence of Syringomycin on Ribonucleic Acid Synthesis
Author(s) -
Donald Penner,
J. E. DeVay,
P. A. Backman
Publication year - 1969
Publication title -
plant physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.554
H-Index - 312
eISSN - 1532-2548
pISSN - 0032-0889
DOI - 10.1104/pp.44.6.806
Subject(s) - polymerase , biochemistry , dna , pseudomonas , rna polymerase , pseudomonas syringae , antibiotics , bacteria , biology , rna , microbiology and biotechnology , primer (cosmetics) , chemistry , gene , genetics , organic chemistry
Syringomycin, a wide-spectrum antibiotic produced by strains of Pseudomonas syringae which cause bacterial canker of peach, was able to bind to salmon sperm and calf thymus deoxyribonucleic acid but not to calf thymus histone; it also inhibited ribonucleic acid polymerase activity. These abilities to bind to deoxyribonucleic acid and to inhibit ribonucleic acid polymerase were inactivated when the phytotoxic and antibiotic properties of syringomycin were inactivated.

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