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Growth Repression of Higher Plants by 2-Pyridinethiol, 1-Oxide.
Author(s) -
A. G. Norman
Publication year - 1957
Publication title -
plant physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.554
H-Index - 312
eISSN - 1532-2548
pISSN - 0032-0889
DOI - 10.1104/pp.32.1.16
Subject(s) - potency , antifungal , broad spectrum , psychological repression , chemistry , antibacterial activity , antibiotics , microorganism , plant growth , natural product , biochemistry , biology , bacteria , microbiology and biotechnology , combinatorial chemistry , in vitro , botany , genetics , gene , gene expression
The compound 2-pyridinethiol, 1-oxide and its salts have been reported to have pronounced antibacterial and antifungal activity of a type that, were it a microbiological product, would cause it to be classed as a broad-spectrum antibiotic (5, 8). This property is shared by a number of other cyclic thiohydroxamic acids, variously substituted, though some are much more active than others. The high potency of this grouping, and. the diversity of microorganisms to which compounds containing it are inhibitory, suggest interference with some essential metabolic process. Furthermore, certain antibiotics of comparable potency have been found to repress growth in some plant systems (1, 3, 4). Accordingly, the activity of 2-pyri-

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