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Protein-protein interactions play critical roles in a wide range of cellular functions. The need to analyze these interactions has spawned a variety of biophysical and biochemical techniques, including coimmunoprecipitation, yeast two-hybrid, bimolecular fluorescence complementation, Forster

A GPI Signal Peptide-Anchored Split-Ubiquitin (GPS) System for Detecting Soluble Bait Protein Interactions at the Membrane