INFLUENCE OF SULFANILAMIDE AND DERIVATIVES ON GROWTH OF LUPINUS ALBUS

The marvelous therapeutic results obtained during the past few years in various infections with sulfanilamide and its derivatives, originating in the epoch-making discoveries of Domagk, have naturally stimulated pharmacological and bacteriological work on these compounds. The pharmacological and toxicological experiments with the sulfamides, however, have been almost exclusively of a z?opharmacological nature, that is, confined to experiments on animals and animal tissues. As these compounds are primarily chemotherapeutic agents affecting in some still inexplicable manner the growth of bacteria, and as bacteria are actually more closely related to lower plants than to lower animals, the writer, who has been making p7ti/?opharmacological studies for many years, determined to investigate the effect of various sulfa-compounds on living plants. The results already obtained are of both theoretical and practical interest. The present paper is a report on the influence of sulfa-drugs on root growth of Lupinus albus seedlings.