High-Throughput Screening for Induced Point Mutations
Author(s) -
Trenton Colbert,
Bradley J. Till,
Rachel Tompa,
Steve Reynolds,
Michael N. Steine,
Anthony T. Yeung,
Claire M. McCallum,
Luca Comai,
Steven Henikoff
Publication year - 2001
Publication title -
plant physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.554
H-Index - 312
eISSN - 1532-2548
pISSN - 0032-0889
DOI - 10.1104/pp.126.2.480
Subject(s) - point mutation , throughput , high throughput screening , genetics , mutation , computational biology , biology , computer science , gene , telecommunications , wireless
With the completion of genome sequencing projects, emphasis in genomics has shifted from analyzing sequences to understanding gene function, and effective reverse genetic strategies are increasingly in demand. Here we report adaptations of the targeting induced local lesions in genomes (TILLING)
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