Nuclear Matrix Attachment Regions and Transgene Expression in Plants | Zendy

Steven Spiker | Zendy; William F. Thompson | Zendy

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Nuclear Matrix Attachment Regions and Transgene Expression in Plants

Author(s) -

Steven Spiker,

William F. Thompson

Publication year - 1996

Publication title -

plant physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.554

H-Index - 312

eISSN - 1532-2548

pISSN - 0032-0889

DOI - 10.1104/pp.110.1.15

Subject(s) - scaffold/matrix attachment region , transgene , nuclear matrix , matrix (chemical analysis) , microbiology and biotechnology , expression (computer science) , genetically modified crops , biology , computational biology , gene expression , genetics , chemistry , computer science , gene , chromatography , chromatin remodeling , chromatin , programming language

DNA sequences called matrix attachment regions (MARs) or scaffold attachment regions (SARs) have re- cently attracted much attention because of their perceived capacity to increase levels of transgene expression and reduce transformant-to-transformant variation of trans- gene expression in both plants and animals. Work with these sequences is in its early stages and data that seem to be contradictory have been presented. We do not intend to resolve these controversies here (this will be accomplished by further research). Rather, we will discuss the hypothe- sized role of MARs in chromatin structure, how MARs are isolated and characterized, what effects MARs have had on the expression of transgenes and the models that have been evoked to explain those effects.

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