Using Combinatorial Design to Study Regulation by Multiple Input Signals. A Tool for Parsimony in the Post-Genomics Era | Zendy

Dennis Shasha | Zendy; Andrei Kouranov | Zendy; Laurence Lejay | Zendy; Michael F. Chou | Zendy; Gloria M. Coruzzi | Zendy

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Using Combinatorial Design to Study Regulation by Multiple Input Signals. A Tool for Parsimony in the Post-Genomics Era

Author(s) -

Dennis Shasha,

Andrei Kouranov,

Laurence Lejay,

Michael F. Chou,

Gloria M. Coruzzi

Publication year - 2001

Publication title -

plant physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.554

H-Index - 312

eISSN - 1532-2548

pISSN - 0032-0889

DOI - 10.1104/pp.010683

Subject(s) - set (abstract data type) , systems biology , computational biology , genomics , computer science , synthetic biology , biology , gene , genome , genetics , programming language

For many systems in biology, genes, pathways, or metabolites are regulated or synthesized in response to multiple “input” signals. Herein, we describe how combinatorial design can be used to define a small set of experiments that will effectively explore the effects of all possible combinations

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