Ronin and Caspases in Embryonic Stem Cells: A New Perspective on Regulation of the Pluripotent State | Zendy

Thomas P. Zwaka | Zendy

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Ronin and Caspases in Embryonic Stem Cells: A New Perspective on Regulation of the Pluripotent State

Author(s) -

Thomas P. Zwaka

Publication year - 2008

Publication title -

cold spring harbor symposia on quantitative biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.615

H-Index - 77

eISSN - 1943-4456

pISSN - 0091-7451

DOI - 10.1101/sqb.2008.73.007

Subject(s) - embryonic stem cell , induced pluripotent stem cell , microbiology and biotechnology , complement (music) , biology , perspective (graphical) , identification (biology) , caspase , computational biology , stem cell , apoptosis , genetics , computer science , programmed cell death , phenotype , gene , botany , artificial intelligence , complementation

Described here are recent discoveries in my laboratory which suggest that the complement of factors needed to direct ES cell pluripotency may be considerably larger than originally thought and may include proteins that act independently of the canonical factors described thus far. They also provide insight into a novel screening method that could be used to accelerate the identification and characterization of such factors.

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