Nuclear Stains | Zendy

J. A. Kiernan | Zendy

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Nuclear Stains

Author(s) -

J. A. Kiernan

Publication year - 2008

Publication title -

cold spring harbor protocols

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.674

H-Index - 51

eISSN - 1940-3402

pISSN - 1559-6095

DOI - 10.1101/pdb.top50

Subject(s) - stain , nucleic acid , chemistry , cytoplasm , cationic polymerization , staining , extracellular , biophysics , biochemistry , pathology , biology , polymer chemistry , medicine

For the study of microscopic anatomy and of pathological material, it is usual to stain sections of tissue in such a way as to impart a dark color to the nuclei of cells and a lighter, contrasting color to the cytoplasm and extracellular structures. Nuclear stains, including cationic, anionic, and metal complexing dyes, are considered in this article. The rationales of the techniques are discussed, but methods of higher chemical specificity (e.g., for nucleic acids, carbohydrates, and functional groups of proteins) are not covered.

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