OMX: A New Platform for Multimodal, Multichannel Wide-Field Imaging
Author(s) -
Ian M. Dobbie,
Emma King,
Richard M. Parton,
Peter M. Carlton,
John W. Sedat,
Jason R. Swedlow,
Ilan Davis
Publication year - 2011
Publication title -
cold spring harbor protocols
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 51
eISSN - 1940-3402
pISSN - 1559-6095
DOI - 10.1101/pdb.top121
Subject(s) - microscope , microscopy , computer science , superresolution , multiphoton fluorescence microscope , nanotechnology , materials science , optics , artificial intelligence , physics , fluorescence microscope , image (mathematics) , fluorescence
This article discusses the design principles and applications of the OMX microscope, a new platform that provides unprecedented mechanical and thermal stabilities coupled with a photon budget that is dramatically improved over traditional microscope platforms. These characteristics make the OMX microscope outstanding for fast live cell imaging and super-resolution imaging. Moreover, its open flexible architecture makes it particularly amenable to adding other modes of microscopy to the platform.
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