Mapping Billions of Short Reads to a Reference Genome | Zendy

JuiHung Hung | Zendy; Zhiping Weng | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Mapping Billions of Short Reads to a Reference Genome

Author(s) -

JuiHung Hung,

Zhiping Weng

Publication year - 2016

Publication title -

cold spring harbor protocols

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.674

H-Index - 51

eISSN - 1940-3402

pISSN - 1559-6095

DOI - 10.1101/pdb.top093153

Subject(s) - reference genome , genome , computational biology , dna sequencer , computer science , dna sequencing , human genome , sequence assembly , biology , dna , genetics , gene , transcriptome , gene expression

Rapid development and commercialization of instruments that can accurately, rapidly, and cheaply sequence billions of DNA bases is revolutionizing molecular biology and medicine. Because a reference genome is usually available, the first bioinformatics challenge presented by the new generation of high-throughput sequencers is the genome mapping problem, where each read is mapped to a reference genome to reveal its location(s). An introduction to mapping algorithms, as well as factors that influence their results, is provided here.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research