Genetic Labeling of Neurons in Mouse Brain
Author(s) -
Z. Josh Huang,
Hiroki Taniguchi,
Miao He,
Sandra J. Kuhlman
Publication year - 2014
Publication title -
cold spring harbor protocols
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 51
eISSN - 1940-3402
pISSN - 1559-6095
DOI - 10.1101/pdb.top080374
Subject(s) - neuroscience , biological neural network , neuronal circuits , neuron , computer science , function (biology) , brain function , neural system , nervous system , biology , microbiology and biotechnology
Mammalian central nervous systems consist of highly diverse types of neurons, which are the functional units of neural circuits. To understand the organization, assembly, and function of neural circuits, it is necessary to develop and to improve technologies that allow efficient and robust visualization of neurons in their native environment in vivo. Here we discuss various genetic strategies for achieving specific and robust neuron labeling in mice.
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