Open AccessThe Nuclear Matrix: Fractionation Techniques and Analysis
Author(s) -
Rosemary H. C. Wilson,
Emma L. Hesketh,
Dawn Coverley
Publication year - 2016
Publication title -
cold spring harbor protocols
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 51
eISSN - 1940-3402
pISSN - 1559-6095
DOI - 10.1101/pdb.top074518
Subject(s) - nuclear matrix , matrix (chemical analysis) , fractionation , computer science , chemistry , chromatography , biochemistry , dna , chromatin
The first descriptions of an insoluble nuclear structure appeared more than 70 years ago, but it is only in recent years that a sophisticated picture of its significance has begun to emerge. Here we introduce multiple methods for the study of the nuclear matrix.
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