Software for Constructing and Verifying Pedigrees within Large Genealogies and an Application to the Old Order Amish of Lancaster County | Zendy

Richa Agarwala | Zendy; Leslie G. Biesecker | Zendy; Katherine Hopkins | Zendy; Clair A. Francomano | Zendy; Alejandro A. Schäffer | Zendy

Open Access

Software for Constructing and Verifying Pedigrees within Large Genealogies and an Application to the Old Order Amish of Lancaster County

Author(s) -

Richa Agarwala,

Leslie G. Biesecker,

Katherine Hopkins,

Clair A. Francomano,

Alejandro A. Schäffer

Publication year - 1998

Publication title -

genome research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.556

H-Index - 297

eISSN - 1549-5469

pISSN - 1088-9051

DOI - 10.1101/gr.8.3.211

Subject(s) - pedigree chart , genealogy , linkage (software) , software , biology , computer science , genetics , theoretical computer science , programming language , gene , history

This paper describes PedHunter, a software package that facilitates creation and verification of pedigrees within large genealogies. A frequent problem in medical genetics is to connect distant relatives with a pedigree. PedHunter uses methods from graph theory to solve two versions of the pedigree connection problem for genealogies as well as other pedigree analysis problems. The pedigrees are produced by PedHunter as files in LINKAGE format ready for linkage analysis. PedHunter uses a relational database of genealogy data, with tables in specified format, for all calculations. The functionality and utility of PedHunter are illustrated by examples using the Amish Genealogy Database (AGDB), which was created for the Old Order Amish community of Lancaster County, Pennsylvania.

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