X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content. | Zendy

Ramaiah Nagaraja | Zendy; Sandra MacMillan | Zendy; Juha Kere | Zendy; Carol Jones | Zendy; Susan H. Griffin | Zendy; Matthew Schmatz | Zendy; Jennifer Terrell | Zendy; Michael Shomaker | Zendy; Christopher Jermak | Zendy; Christian Hott | Zendy; Mochubeloa W.J. Masisi | Zendy; Steven Mumm | Zendy; Anand Srivastava | Zendy; Giuseppe Pilia | Zendy; T. Featherstone | Zendy; Richard Mazzarella | Zendy; S Kesterson | Zendy; Brigid McCauley | Zendy; Brian Railey | Zendy; Frank W. Burough | Zendy; Volker Nowotny | Zendy; Michele D’Urso | Zendy; David States | Zendy; Buddy Brownstein | Zendy; David Schlessinger | Zendy

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X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content.

Author(s) -

Ramaiah Nagaraja,

Sandra MacMillan,

Juha Kere,

Carol Jones,

Susan H. Griffin,

Matthew Schmatz,

Jennifer Terrell,

Michael Shomaker,

Christopher Jermak,

Christian Hott,

Mochubeloa W.J. Masisi,

Steven Mumm,

Anand Srivastava,

Giuseppe Pilia,

T. Featherstone,

Richard Mazzarella,

S Kesterson,

Brigid McCauley,

Brian Railey,

Frank W. Burough,

Volker Nowotny,

Michele D’Urso,

David States,

Buddy Brownstein,

David Schlessinger

Publication year - 1997

Publication title -

genome research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.556

H-Index - 297

eISSN - 1549-5469

pISSN - 1088-9051

DOI - 10.1101/gr.7.3.210

Subject(s) - biology , xist , genetics , recombination , x chromosome , gene mapping , chromosome , gc content , gene , homology (biology) , locus (genetics) , x inactivation , genome

A YAC/STS map of the X chromosome has reached an inter-STS resolution of 75 kb. The map density is sufficient to provide YACs or other large-insert clones that are cross-validated as sequencing substrates across the chromosome. Marker density also permits estimates of regional gene content and a detailed comparison of genetic and physical map distances. Five regions are detected with relatively high G + C, correlated with gene richness; and a 17-Mb region with very low recombination is revealed between the Xq13.3 [XIST] and Xq21.3 XY homology loci.

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