IMAGE cDNA Clones, UniGene Clustering, and ACeDB: An Integrated Resource for Expressed Sequence Information | Zendy

Greg Miller | Zendy; Rainer Fuchs | Zendy; Eric C. Lai | Zendy

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IMAGE cDNA Clones, UniGene Clustering, and ACeDB: An Integrated Resource for Expressed Sequence Information

Author(s) -

Greg Miller,

Rainer Fuchs,

Eric C. Lai

Publication year - 1997

Publication title -

genome research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.556

H-Index - 297

eISSN - 1549-5469

pISSN - 1088-9051

DOI - 10.1101/gr.7.10.1027

Subject(s) - unigene , expressed sequence tag , biology , cdna library , complementary dna , insert (composites) , computational biology , genetics , cloning (programming) , sequence analysis , gene , computer science , mechanical engineering , programming language , engineering

In this study we describe a new information resource that provides integrated access to information on IMAGE (integrated molecular analysis of genomes and their expression) cDNA library clones and derived expressed sequence tags (ESTs). We have developed an automated procedure that collates data from various public sources into a single ACeDB database. This database is a valuable tool for electronic cloning experiments and gene expression studies. It allows researchers to find information about cDNA libraries, plate addresses, insert sizes, and sequence data for IMAGE clones, the assignment of ESTs to UniGene clusters, and the chromosomal location of those genes in an efficient, graphically oriented manner.

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