A contiguous high-resolution radiation hybrid map of 44 loci from the distal portion of the long arm of human chromosome 5. | Zendy

Janet A. Warrington | Zendy; John J. Wasmuth | Zendy

Open Access

A contiguous high-resolution radiation hybrid map of 44 loci from the distal portion of the long arm of human chromosome 5.

Author(s) -

Janet A. Warrington,

John J. Wasmuth

Publication year - 1996

Publication title -

genome research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.556

H-Index - 297

eISSN - 1549-5469

pISSN - 1088-9051

DOI - 10.1101/gr.6.7.628

Subject(s) - biology , radiation hybrid mapping , gene mapping , positional cloning , sequence tagged site , genetics , chromosome , physical mapping , human genome , long arm , gene , genome , computational biology , locus (genetics)

A contiguous high-resolution map of 44 loci from a 35-Mb portion of the distal region of the long arm of human chromosome 5, q21-q35, was produced using radiation hybrid (RH) mapping in conjunction with a natural deletion mapping panel. The map includes 30 genes, four sequence-tagged site (STS) loci, and 10 DNA markers. Newly mapped markers fill two gap regions that were present in previous maps, between markers FER-IL4 and IL3-IL9. Identifying the position of genes on the physical map aids in positional cloning efforts and contributes to our understanding of the overall organization of the human genome.

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