Galaxy: A platform for interactive large-scale genome analysis
Author(s) -
Belinda Giardine,
Cathy Riemer,
Ross C. Hardison,
Richard Burhans,
Laura Elnitski,
Prachi Shah,
Yi Zhang,
Daniel Blankenberg,
István Albert,
James Taylor,
Webb Miller,
W. James Kent,
Anton Nekrutenko
Publication year - 2005
Publication title -
genome research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.556
H-Index - 297
eISSN - 1549-5469
pISSN - 1088-9051
DOI - 10.1101/gr.4086505
Subject(s) - annotation , biology , computer science , genome , galaxy , simple (philosophy) , visualization , computational biology , world wide web , information retrieval , bioinformatics , data mining , astrophysics , genetics , gene , physics , philosophy , epistemology
Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu.
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