Quality assurance and use of PCR in clinical trials. | Zendy

P S Reichelderfer | Zendy; J. Brooks Jackson | Zendy

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Quality assurance and use of PCR in clinical trials.

Author(s) -

P S Reichelderfer,

J. Brooks Jackson

Publication year - 1994

Publication title -

genome research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.556

H-Index - 297

eISSN - 1549-5469

pISSN - 1088-9051

DOI - 10.1101/gr.4.3.s141

Subject(s) - biology , quality assurance , pathology , medicine , external quality assessment

Qualitative and quantitative HIV-1 DNA and RNA PCR assays are proving to be useful in the diagnosis of HIV-1 infection in infants and in assessing the in vivo antiviral activity of new therapies and regimens in clinical trials. The use of these standardized commercial assays in conjunction with an external quality assurance program has ensured that results from different laboratories are comparable. In addition, real-time proficiency monitoring has the potential to detect problems immediately before patient data are compromised.

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