The NIH Human Microbiome Project
Author(s) -
Jane L. Peterson,
Susan Garges,
Maria Y. Giovanni,
Pamela McInnes,
Lu Wang,
Jeffery A. Schloss,
Vivien Bonazzi,
Jean E. McEwen,
Kris A. Wetterstrand,
Carolyn Deal,
Carl C. Baker,
Valentina Di Francesco,
T. Kevin Howcroft,
Robert W. Karp,
R. Dwayne Lunsford,
Christopher Wellington,
Tsegahiwot Belachew,
Michael Wright,
Christina Giblin,
Hagit David,
Melody Mills,
Rachelle Salomon,
Christopher Mullins,
Beena Akolkar,
Lisa Begg,
Cindy D. Davis,
Lindsey Grandison,
Michael C. Humble,
Jag Khalsa,
A. Roger Little,
Hannah Peavy,
Carol H. Pontzer,
Matthew E. Portnoy,
Michael H. Sayre,
Pamela StarkeReed,
Samir Zakhari,
Jennifer Read,
Bracie Watson,
Mark S. Guyer
Publication year - 2009
Publication title -
genome research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.556
H-Index - 297
eISSN - 1549-5469
pISSN - 1088-9051
DOI - 10.1101/gr.096651.109
Subject(s) - microbiome , human microbiome project , biology , human microbiome , human health , resource (disambiguation) , human disease , data science , engineering ethics , computational biology , bioinformatics , computer science , environmental health , engineering , genetics , medicine , gene , computer network
The Human Microbiome Project (HMP), funded as an initiative of the NIH Roadmap for Biomedical Research (http://nihroadmap.nih.gov), is a multi-component community resource. The goals of the HMP are: (1) to take advantage of new, high-throughput technologies to characterize the human microbiome more fully by studying samples from multiple body sites from each of at least 250 "normal" volunteers; (2) to determine whether there are associations between changes in the microbiome and health/disease by studying several different medical conditions; and (3) to provide both a standardized data resource and new technological approaches to enable such studies to be undertaken broadly in the scientific community. The ethical, legal, and social implications of such research are being systematically studied as well. The ultimate objective of the HMP is to demonstrate that there are opportunities to improve human health through monitoring or manipulation of the human microbiome. The history and implementation of this new program are described here.
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