Chemoprevention in Prostate Cancer: Current Perspective and Future Directions
Author(s) -
J. Ricardo Rivero,
Ian M. Thompson,
Michael A. Liss,
Dharam Kaushik
Publication year - 2018
Publication title -
cold spring harbor perspectives in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.853
H-Index - 105
eISSN - 2472-5412
pISSN - 2157-1422
DOI - 10.1101/cshperspect.a030494
Subject(s) - prostate cancer , medicine , prostate , disease , oncology , cancer , cancer research
Chemoprevention of prostate cancer aims to reduce the mortality as well as the public burden of overdetection, which increases anxiety, cost, and morbidity related to the disease. The role of 5-α-reductase inhibitors has been well investigated and shown to decrease the risk of prostate cancer. No current evidence exists to encourage the use of nutrients or vitamins as chemopreventive agents. The modulation of inflammation is one of the most promising targets for chemoprevention of prostate cancer.
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