Molecular Cross-Talk at the Feto–Maternal Interface | Zendy

Gendie E. Lash | Zendy

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Molecular Cross-Talk at the Feto–Maternal Interface

Author(s) -

Gendie E. Lash

Publication year - 2015

Publication title -

cold spring harbor perspectives in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.853

H-Index - 105

eISSN - 2472-5412

pISSN - 2157-1422

DOI - 10.1101/cshperspect.a023010

Subject(s) - trophoblast , spiral artery , pregnancy , spiral (railway) , interface (matter) , medicine , microbiology and biotechnology , biology , placenta , fetus , engineering , mechanical engineering , pulmonary surfactant , gibbs isotherm , genetics , biochemistry

Molecular cross-talk at the feto-maternal interface occurs between many different cell types, including uterine leukocytes, extravillous trophoblast cells, and uterine spiral arteries, is essential for the establishment and maintenance of pregnancy. This review concentrates on human pregnancy and examines three main areas in which cross-talk occurs; immune tolerance, regulation of extravillous trophoblast invasion, and remodeling of the uterine spiral arteries.

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