Endocytosis of Viruses and Bacteria
Author(s) -
Pascale Cossart,
Ari Helenius
Publication year - 2014
Publication title -
cold spring harbor perspectives in biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.011
H-Index - 173
ISSN - 1943-0264
DOI - 10.1101/cshperspect.a016972
Subject(s) - biology , endocytic cycle , endocytosis , intracellular parasite , bacteria , microbiology and biotechnology , organelle , cytosol , intracellular , viral replication , virus , virology , cell , genetics , biochemistry , enzyme
Of the many pathogens that infect humans and animals, a large number use cells of the host organism as protected sites for replication. To reach the relevant intracellular compartments, they take advantage of the endocytosis machinery and exploit the network of endocytic organelles for penetration into the cytosol or as sites of replication. In this review, we discuss the endocytic entry processes used by viruses and bacteria and compare the strategies used by these dissimilar classes of pathogens.
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