Alzheimer Disease in 2020 | Zendy

David M. Holtzman | Zendy; EvaMaria Mandelkow | Zendy; D. J. Selkoe | Zendy

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Alzheimer Disease in 2020

Author(s) -

David M. Holtzman,

EvaMaria Mandelkow,

D. J. Selkoe

Publication year - 2012

Publication title -

cold spring harbor perspectives in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.853

H-Index - 105

eISSN - 2472-5412

pISSN - 2157-1422

DOI - 10.1101/cshperspect.a011585

Subject(s) - principal (computer security) , disease , psychology , neuroscience , cognitive science , data science , epistemology , medicine , computer science , philosophy , pathology , operating system

Remarkable advances in unraveling the biological underpinnings of Alzheimer disease (AD) have occurred during the last 25 years. Despite this, we have made only the smallest of dents in the development of truly disease-modifying treatments. What will change over the next 10 years? While the answer is not clear, we make several predictions on the state of the field in 2020, based on the rich knowledge described in the other contributions in this collection. As such, our predictions represent some of the principal unresolved questions that we believe deserve special investigative attention in the coming decade.

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