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Lipoxins: A Novel Regulator in Embryo Implantation
Author(s) -
Jing Xiong,
Pan Zeng,
Duyun Ye
Publication year - 2011
Publication title -
the scientific world journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.453
H-Index - 93
eISSN - 2356-6140
pISSN - 1537-744X
DOI - 10.1100/tsw.2011.15
Subject(s) - regulator , endometrium , blastocyst , embryo , leukemia inhibitory factor , homeobox , inflammation , decidua , biology , medicine , pregnancy , bioinformatics , microbiology and biotechnology , embryogenesis , immunology , fetus , genetics , gene , transcription factor , placenta , interleukin 6
Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity, including leukemia inhibitory factor, calcitonin, and homeobox A10. There is a close relationship between implantation and inflammation. Lipoxins, important in the resolution of inflammation, may be a potential regulator in implantation. Here we discuss the hypothesis that lipoxins may work as a novel regulator in embryo implantation and the possible molecular mechanisms.

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