Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy | Zendy

Luca Fusi | Zendy; A. Purohit | Zendy; Jan J. Brosens | Zendy; L. W. Lawrence Woo | Zendy; B. V. L. POTTER | Zendy; Michael Reed | Zendy

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Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy

Author(s) -

Luca Fusi,

A. Purohit,

Jan J. Brosens,

L. W. Lawrence Woo,

B. V. L. POTTER,

Michael Reed

Publication year - 2008

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/tsw.2008.164

Subject(s) - endometriosis , steroid sulfatase , infertility , estrogen , medicine , steroid , medical therapy , endocrinology , bioinformatics , pharmacology , biology , pregnancy , hormone , genetics

Endometriosis is a common and debilitating condition of women in their reproductive age that is associated with pain and infertility. Current medical treatments are only partially effective and associated with wide-ranging side effects. New understanding of local estrogen production by endometriotic tissue and the availability of powerful suppressing drugs may herald a new era in the treatment of this condition.

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