Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens | Zendy

Christine Wu | Zendy; Parmjeet Randhawa | Zendy; Jerry McCauley | Zendy

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Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens

Author(s) -

Christine Wu,

Parmjeet Randhawa,

Jerry McCauley

Publication year - 2006

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/tsw.2006.93

Subject(s) - immunosuppression , bk virus , medicine , transplantation , kidney transplantation , nephropathy , genitourinary system , disease , polyomavirus infections , kidney , intensive care medicine , immunology , urology , endocrinology , diabetes mellitus

BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a significant cause of genitourinary disease and potential graft loss in the kidney transplant patient. In this review, we discuss the risk factors, available methods of diagnosis and therapeutic monitoring, and current approaches to therapy of BKVN.

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