Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
Author(s) -
Kerstin Hellwig,
Carsten Lukas,
N. Brune,
Volker Hoffmann,
Sebastian Schimrigk,
H. Przuntek,
Thomas Müller
Publication year - 2006
Publication title -
the scientific world journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.453
H-Index - 93
eISSN - 2356-6140
pISSN - 1537-744X
DOI - 10.1100/tsw.2006.86
Subject(s) - medicine , multiple sclerosis , triamcinolone acetonide , dysesthesia , anesthesia , intrathecal , lesion , relapsing remitting , gabapentin , spinal cord , surgery , pathology , immunology , psychiatry , alternative medicine
We describe four patients with relapsing remitting multiple sclerosis (RRMS) who experienced a relapse with acute onset of painful sensations. Pain sensations disappeared in two of them and markedly reduced in the other ones after repeat application of intrathecal triamcinolone acetonide (TCA) following a prior unsuccessful treatment with intravenous steroids. TCA administration was well tolerated and no serious side effects occurred. Repeated intrathecal TCA injection may provide a substantial benefit in RRMS patients with acute onset of pain due to an inflammatory lesion within the spinal cord.
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