Chromatin Modification and Remodeling in Heart Development | Zendy

Paul Delgado-Olguı́n | Zendy; Jun Takeuchi | Zendy; Benoit G. Bruneau | Zendy

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Chromatin Modification and Remodeling in Heart Development

Author(s) -

Paul Delgado-Olguı́n,

Jun Takeuchi,

Benoit G. Bruneau

Publication year - 2006

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/tsw.2006.315

Subject(s) - chromatin , chromatin remodeling , transcription factor , organogenesis , microbiology and biotechnology , biology , function (biology) , transcription (linguistics) , context (archaeology) , chia pet , computational biology , gene , genetics , paleontology , linguistics , philosophy

In organogenesis, cell types are specified from determined precursors as morphogenetic patterning takes place. These events are largely controlled by tissue-specific transcription factors. These transcription factors must function within the context of chromatin to activate or repress target genes. Recent evidence suggests that chromatin-remodeling and -modifying factors may have tissue-specific function. Here we review the potential roles for chromatin-remodeling and -modifying proteins in the development of the mammalian heart.

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