Correlating Yeast Cell Stress Physiology to Changes in the Cell Surface Morphology: Atomic Force Microscopic Studies | Zendy

Elisabetta Canetta | Zendy; Graeme M. Walker | Zendy; Ashok K. Adya | Zendy

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Correlating Yeast Cell Stress Physiology to Changes in the Cell Surface Morphology: Atomic Force Microscopic Studies

Author(s) -

Elisabetta Canetta,

Graeme M. Walker,

Ashok K. Adya

Publication year - 2006

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/tsw.2006.166

Subject(s) - atomic force microscopy , yeast , schizosaccharomyces pombe , cell , saccharomyces cerevisiae , cell physiology , biophysics , morphology (biology) , schizosaccharomyces , substrate (aquarium) , eukaryotic cell , nanotechnology , adhesion , cell adhesion , microbiology and biotechnology , chemistry , biology , materials science , biochemistry , ecology , genetics , organic chemistry

Atomic Force Microscopy (AFM) has emerged as a powerful biophysical tool in biotechnology and medicine to investigate the morphological, physical, and mechanical properties of yeasts and other biological systems. However, properties such as, yeasts' response to environmental stresses, metabolic activities of pathogenic yeasts, cell-cell/cell-substrate adhesion, and cell-flocculation have rarely been investigated so far by using biophysical tools. Our recent results obtained by AFM on one strain each of Saccharomyces cerevisiae and Schizosaccharomyces pombe show a clear correlation between the physiology of environmentally stressed yeasts and the changes in their surface morphology. The future directions of the AFM related techniques in relation to yeasts are also discussed.

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