Volume Transmission and Pain Perception | Zendy

Gilberto CastañedaHernández | Zendy; Paul BachyRita | Zendy

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Volume Transmission and Pain Perception

Author(s) -

Gilberto CastañedaHernández,

Paul BachyRita

Publication year - 2003

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/tsw.2003.53

Subject(s) - neuroscience , perception , extracellular , transmission (telecommunications) , neuroplasticity , relevance (law) , pain perception , extracellular fluid , neurotransmission , perspective (graphical) , receptor , volume (thermodynamics) , diffusion , medicine , computer science , psychology , anesthesia , biology , artificial intelligence , microbiology and biotechnology , physics , telecommunications , quantum mechanics , political science , law , thermodynamics

Volume transmission (VT) is the diffusion through the brain extracellular fluid of neurotransmitters released at points that may be remote from the target cells with the resulting activation of extrasynaptic receptors. VT appears to play multiple roles in the brain in normal and abnormal activity, brain plasticity and drug actions. The relevance of VT to pain perception has been explored in this review.

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