A Role for Exocytosis in the Spatial Regulationof Actin Organization | Zendy

XiangDong Gao | Zendy; Štefan Albert | Zendy

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A Role for Exocytosis in the Spatial Regulationof Actin Organization

Author(s) -

XiangDong Gao,

Štefan Albert

Publication year - 2003

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/tsw.2003.119

Subject(s) - exocytosis , microbiology and biotechnology , actin cytoskeleton , endocytosis , actin , cytoskeleton , actin remodeling , biology , formins , secretion , cell , genetics , biochemistry

The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role in the spatial regulation of actin organization. Our findings suggest that the actin cytoskeleton, exocytosis, and perhaps endocytosis, may depend on each other for efficiency and reinforce each other.

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