Open AccessThermodynamic Molecular Switch in Sequence-Specific Hydrophobic Interactions
Author(s) -
Paul W. Chun
Publication year - 2002
Publication title -
the scientific world journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.453
H-Index - 93
eISSN - 2356-6140
pISSN - 1537-744X
DOI - 10.1100/tsw.2002.46
Subject(s) - sequence (biology) , molecular switch , computer science , chemistry , molecule , biochemistry , organic chemistry
minimum in the Gibbs free energy change of reaction, and hence, a maximum in the related . This presentation demonstrates the existence of a thermodynamic molecular switch in the pairwise, sequence-specific hydrophobic interaction of Ile-Ile, Leu-Ile, Val-Leu, or Ala-Leu over the temperature range of 273–333 K, as reported by Nemethy and Scheraga[1] and analyzed by the Plank-Benzinger methodology[2–7].
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