Electron Tomography: Towards Visualizing Supramolecular Architecture Inside Cells | Zendy

Wolfgang Baumeister | Zendy; Ohad Medalia | Zendy; J. Boehm | Zendy; Stephan Nickell | Zendy; S. A. Frangakis | Zendy

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Electron Tomography: Towards Visualizing Supramolecular Architecture Inside Cells

Author(s) -

Wolfgang Baumeister,

Ohad Medalia,

J. Boehm,

Stephan Nickell,

S. A. Frangakis

Publication year - 2002

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/tsw.2002.42

Subject(s) - computer science , tomography , architecture , electron tomography , supramolecular chemistry , data science , nanotechnology , materials science , chemistry , physics , crystallography , optics , geography , archaeology , scanning transmission electron microscopy , transmission electron microscopy , crystal structure

. It has long been a dream of cell biologists to catch a glimpse of the molecular architecture inside living cells, so far largely an uncharted territory. In addition to relatively robust molecular machines, these are undoubtedly many ensembles of macromolecules which jointly perform vital functions, but are held together by forces too weak to withstand conventional biochemical isolation and purification procedures[1,2].

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