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Formation of Neural Precursor Cell Populations by Differentiation of Embryonic Stem Cells In Vitro
Author(s) -
Joy Rathjen,
Peter D. Rathjen
Publication year - 2002
Publication title -
the scientific world journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.453
H-Index - 93
eISSN - 2356-6140
pISSN - 1537-744X
DOI - 10.1100/tsw.2002.134
Subject(s) - embryonic stem cell , cellular differentiation , stem cell , biology , precursor cell , microbiology and biotechnology , neural stem cell , in vitro , population , computational biology , neuroscience , computer science , genetics , gene , medicine , environmental health
Recent interest in the generation of neural lineages by differentiation of embryonic stem cells arises from the opportunities represented by a developmentally normal, unlimited source of material that can be manipulated genetically with precision. Several experimental approaches, which differ conceptually, in the route of differentiation and the characteristics of the resulting cell population have been reported. In this review we undertake a comparative analysis of these approaches and their suitability for experimental investigation or implantation.

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