A Novel Nonpeptide CGRP Receptor Antagonist, ‘Compound 1’ (WO98/11128) Is a High Affinity Competitive Antagonist at the CGRP1 Receptor in Human Coronary Arteries
Author(s) -
Philip Hasbak,
Ole Saetrum Opgaard,
Karen Eskesen,
Søren Schifter,
Henrik Arendrup,
J. Longmore,
Lars Edvinsson
Publication year - 2001
Publication title -
the scientific world journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.453
H-Index - 93
eISSN - 2356-6140
pISSN - 1537-744X
DOI - 10.1100/tsw.2001.416
Subject(s) - antagonist , competitive antagonist , calcitonin gene related peptide , receptor antagonist , receptor , pharmacology , coronary arteries , medicine , chemistry , artery , neuropeptide
P. Hasbak, O. Saetrum Opgaard, K. Eskesen, S. Schifter, H. Arendrup, J. Longmore, and L. Edvinsson Department of Clinical Experimental Research, University Hospital of Copenhagen, Glostrup, Denmark; Department of Clinical Physiology and Nuclear Medicine, University Hospital of Copenhagen, Glostrup, Denmark; Department of Pharmacology, College of Medicine, University of California at Irvine, Irvine, CA; Department of Thoracic Surgery, Rigshospitalet, Copenhagen, Denmark; Merck Sharp & Dohme, Neuroscience Research Centre, Harlow, Essex, U.K.
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